Topical anaesthetics are widely used in dermatological procedures. Application of topical anaesthetics have proven to decrease pain and discomfort associated with these procedures, including cosmetic procedures, such as filler injectables, laser hair removal, dental procedures and others.
Benzocaine, Lidocaine and Tetracaine (BLT) is a combination of topical anaesthetics used in the application to accessible mucous membranes except the eyes. BLT cream prepared by The Pharmacy Inc Compounding Pharmacy is a uniquely formulated prescription medication. It is formulated to increase absorption through the skin and is usually applied to unbroken skin 1 0 -15 minutes before dry procedure. It is more potent and lasts longer than any commercially available topical anaesthetic.
Mode of Action
BLT are local anaesthetics that cause a reversible blockade of nerve conduction by decreasing nerve membrane permeability to sodium. This decreases the rate of membrane depolarization, thereby increasing the threshold for electrical excitability.
The blockade affects all nerve fibers in the following sequence: autonomic, sensory and motor, with effects diminishing in reverse order. Clinically, loss of function occurs as follows: pain, temperature, touch, proprioception, and skeletal muscle tone.
Direct nerve membrane penetration is necessary for effective anaesthesia, which is achieved by applying the anaesthetic topically to the area to be anaesthetized. While systemic absorption of local anaesthetics can produce effects on the central nervous and cardiovascular systems, systemic absorption of BLT is expected to be minimal with appropriate use.
Topical application of BLT to mucosal tissue produced anaesthesia in approximately 1 minute and the duration of action is 30 to 60 minutes.
Systemic absorption from topical preparations is minimal, but application to broken or bruised skin greatly increases absorption.
Some compounded formulas require a prescription from the doctor. Contact our pharmacy or one of our sales representatives for more information.